MicroRNA-130b Promotes Tumor Development and Is Associated with Poor Prognosis in Colorectal Cancer

MicroRNA-130b (miR-130b) is involved in several biologic processes; its role in colorectal tumorigenesis has not been addressed so far. Herein, we demonstrate that miR-130b up-regulation exhibits clinical relevance as it is linked to advanced colorectal cancers (CRCs), poor patients' prognosis...

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Bibliographic Details
Main Authors: Tommaso Colangelo, Alessandra Fucci, Carolina Votino, Lina Sabatino, Massimo Pancione, Carmelo Laudanna, Monica Binaschi, Mario Bigioni, Carlo Alberto Maggi, Domenico Parente, Nicola Forte, Vittorio Colantuoni
Format: Article
Language:English
Published: Elsevier 2013-09-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S147655861380019X