1,3-Dicaffeoylquinic Acid as an Active Compound of <i>Arctium lappa</i> Root Extract Ameliorates Depressive-Like Behavior by Regulating Hippocampal Nitric Oxide Synthesis in Ovariectomized Mice

1,3-Dicaffeoylquinic Acid as an Active Compound of <i>Arctium lappa</i> Root Extract Ameliorates Depressive-Like Behavior by Regulating Hippocampal Nitric Oxide Synthesis in Ovariectomized Mice

Menopause is a risk factor for depression. Although 1,3-dicaffeoylquinic acid (1,3-diCQA), a phenolic compound in <i>Arctium lappa</i> (<i>A. lappa</i>) root, has various health benefits, its effects on menopausal depression remain to be determined. Therefore, this study inve...

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Bibliographic Details
Main Authors: Dong Wook Lim, Minji Kim, Minseok Yoon, Jaekwang Lee, Changho Lee, Min Young Um
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Antioxidants
Subjects:
<i>Arctium lappa</i> root
menopause
depression
nitric oxide
neuronal nitric oxide synthase
ERK–CREB–BDNF signaling
Online Access:https://www.mdpi.com/2076-3921/10/8/1281

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