Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse

Characterization and function of the human macrophage dopaminergic system: implications for CNS disease and drug abuse

<p>Abstract</p> <p>Background</p> <p>Perivascular macrophages and microglia are critical to CNS function. Drugs of abuse increase extracellular dopamine in the CNS, exposing these cells to elevated levels of dopamine. In rodent macrophages and human T-cells, dopamine wa...

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Bibliographic Details
Main Authors: Gaskill Peter J, Carvallo Loreto, Eugenin Eliseo A, Berman Joan W
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Journal of Neuroinflammation
Subjects:
Monocyte derived macrophage
Dopamine
Drug abuse
Cytokine
Neuroinflammation dopamine receptor
Dopamine transporter
Tyrosine hydroxylase
Aromatic amino acid decarboxylase
Online Access:http://www.jneuroinflammation.com/content/9/1/203

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http://www.jneuroinflammation.com/content/9/1/203

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