Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating

The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding...

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Main Authors:	Kamal Usef Sadek, Ramadan Ahmed Mekheimer, Tahany Mahmoud Mohamed, Moustafa Sherief Moustafa, Mohamed Hilmy Elnagdi
Format:	Article
Language:	English
Published:	Beilstein-Institut 2012-01-01
Series:	Beilstein Journal of Organic Chemistry
Subjects:	aminopyrazoles dimedone DMFDMA regioselectivity
Online Access:	https://doi.org/10.3762/bjoc.8.3

id	doaj-ad558acef5f14112903b9a232ea8ce55
record_format	Article
spelling	doaj-ad558acef5f14112903b9a232ea8ce552021-02-02T07:50:16ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972012-01-0181182410.3762/bjoc.8.31860-5397-8-3Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heatingKamal Usef Sadek0Ramadan Ahmed Mekheimer1Tahany Mahmoud Mohamed2Moustafa Sherief Moustafa3Mohamed Hilmy Elnagdi4Chemistry Department, Faculty of Science, El-Minia University, El-Minia 61519, EgyptChemistry Department, Faculty of Science, El-Minia University, El-Minia 61519, EgyptChemistry Department, Faculty of Science, El-Minia University, El-Minia 61519, EgyptChemistry Department, Faculty of Science, Kuwait University, PO Box 5969, Safat, 13060 KuwaitChemistry Department, Faculty of Science, Kuwait University, PO Box 5969, Safat, 13060 KuwaitThe multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding dihydropyrazolo[5,1-b]quinazolin-8(5H)-ones 4.https://doi.org/10.3762/bjoc.8.3aminopyrazolesdimedoneDMFDMAregioselectivity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Kamal Usef Sadek Ramadan Ahmed Mekheimer Tahany Mahmoud Mohamed Moustafa Sherief Moustafa Mohamed Hilmy Elnagdi
spellingShingle	Kamal Usef Sadek Ramadan Ahmed Mekheimer Tahany Mahmoud Mohamed Moustafa Sherief Moustafa Mohamed Hilmy Elnagdi Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating Beilstein Journal of Organic Chemistry aminopyrazoles dimedone DMFDMA regioselectivity
author_facet	Kamal Usef Sadek Ramadan Ahmed Mekheimer Tahany Mahmoud Mohamed Moustafa Sherief Moustafa Mohamed Hilmy Elnagdi
author_sort	Kamal Usef Sadek
title	Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
title_short	Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
title_full	Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
title_fullStr	Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
title_full_unstemmed	Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
title_sort	regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating
publisher	Beilstein-Institut
series	Beilstein Journal of Organic Chemistry
issn	1860-5397
publishDate	2012-01-01
description	The multicomponent reaction of 5-aminopyrazole derivatives with cyclic 1,3-dicarbonyl compounds and dimethylformamide dimethylacetal (DMFDMA) in DMF at 150 °C under controlled microwave heating afforded regioselectively 8,9-dihydropyrazolo[1,5-a]quinazolin-6(7H)-ones 6 rather than the corresponding dihydropyrazolo[5,1-b]quinazolin-8(5H)-ones 4.
topic	aminopyrazoles dimedone DMFDMA regioselectivity
url	https://doi.org/10.3762/bjoc.8.3
work_keys_str_mv	AT kamalusefsadek regioselectivityinthemulticomponentreactionof5aminopyrazolescyclic13diketonesanddimethylformamidedimethylacetalundercontrolledmicrowaveheating AT ramadanahmedmekheimer regioselectivityinthemulticomponentreactionof5aminopyrazolescyclic13diketonesanddimethylformamidedimethylacetalundercontrolledmicrowaveheating AT tahanymahmoudmohamed regioselectivityinthemulticomponentreactionof5aminopyrazolescyclic13diketonesanddimethylformamidedimethylacetalundercontrolledmicrowaveheating AT moustafasheriefmoustafa regioselectivityinthemulticomponentreactionof5aminopyrazolescyclic13diketonesanddimethylformamidedimethylacetalundercontrolledmicrowaveheating AT mohamedhilmyelnagdi regioselectivityinthemulticomponentreactionof5aminopyrazolescyclic13diketonesanddimethylformamidedimethylacetalundercontrolledmicrowaveheating
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Regioselectivity in the multicomponent reaction of 5-aminopyrazoles, cyclic 1,3-diketones and dimethylformamide dimethylacetal under controlled microwave heating

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