Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes.
Although endosomal compartments have been suggested to play a role in unconventional protein secretion, there is scarce experimental evidence for such involvement. Here we report that recycling endosomes are essential for externalization of cytoplasmic secretory protein tissue transglutaminase (tTG)...
Main Authors: | Evgeny A Zemskov, Irina Mikhailenko, Ru-Ching Hsia, Liubov Zaritskaya, Alexey M Belkin |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-04-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3083433?pdf=render |
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