A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis

A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis

Ochratoxin A (OTA) exposure via ingestion and inhalation has been described in the literature to cause kidney disease in both animals and humans. This paper reviews Ochratoxin A and its relationship to human health and kidney disease with a focus on a possible association with focal segmental glomer...

Full description

Bibliographic Details
Main Authors: Janette H. Hope, Bradley E. Hope
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Environmental and Public Health
Online Access:http://dx.doi.org/10.1155/2012/835059
id doaj-ad5183a34cc14521a8039ef589168499
record_format Article
spelling doaj-ad5183a34cc14521a8039ef5891684992020-11-24T22:35:22ZengHindawi LimitedJournal of Environmental and Public Health1687-98051687-98132012-01-01201210.1155/2012/835059835059A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental GlomerulosclerosisJanette H. Hope0Bradley E. Hope1Environmental Medicine, 304 West Los Olivos Street, Santa Barbara, CA 93105, USAAmerican Indian Health and Services, 4141 State Street B-4, Santa Barbara, CA 93110, USAOchratoxin A (OTA) exposure via ingestion and inhalation has been described in the literature to cause kidney disease in both animals and humans. This paper reviews Ochratoxin A and its relationship to human health and kidney disease with a focus on a possible association with focal segmental glomerulosclerosis (FSGS) in humans. Prevention and treatment strategies for OTA-induced illness are also discussed, including cholestyramine, a bile-acid-binding resin used as a sequestrant to reduce the enterohepatic recirculation of OTA.http://dx.doi.org/10.1155/2012/835059
collection DOAJ
language English
format Article
sources DOAJ
author Janette H. Hope
Bradley E. Hope
spellingShingle Janette H. Hope
Bradley E. Hope
A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis
Journal of Environmental and Public Health
author_facet Janette H. Hope
Bradley E. Hope
author_sort Janette H. Hope
title A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis
title_short A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis
title_full A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis
title_fullStr A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis
title_full_unstemmed A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis
title_sort review of the diagnosis and treatment of ochratoxin a inhalational exposure associated with human illness and kidney disease including focal segmental glomerulosclerosis
publisher Hindawi Limited
series Journal of Environmental and Public Health
issn 1687-9805
1687-9813
publishDate 2012-01-01
description Ochratoxin A (OTA) exposure via ingestion and inhalation has been described in the literature to cause kidney disease in both animals and humans. This paper reviews Ochratoxin A and its relationship to human health and kidney disease with a focus on a possible association with focal segmental glomerulosclerosis (FSGS) in humans. Prevention and treatment strategies for OTA-induced illness are also discussed, including cholestyramine, a bile-acid-binding resin used as a sequestrant to reduce the enterohepatic recirculation of OTA.
url http://dx.doi.org/10.1155/2012/835059
work_keys_str_mv AT janettehhope areviewofthediagnosisandtreatmentofochratoxinainhalationalexposureassociatedwithhumanillnessandkidneydiseaseincludingfocalsegmentalglomerulosclerosis
AT bradleyehope areviewofthediagnosisandtreatmentofochratoxinainhalationalexposureassociatedwithhumanillnessandkidneydiseaseincludingfocalsegmentalglomerulosclerosis
AT janettehhope reviewofthediagnosisandtreatmentofochratoxinainhalationalexposureassociatedwithhumanillnessandkidneydiseaseincludingfocalsegmentalglomerulosclerosis
AT bradleyehope reviewofthediagnosisandtreatmentofochratoxinainhalationalexposureassociatedwithhumanillnessandkidneydiseaseincludingfocalsegmentalglomerulosclerosis
_version_ 1725723714113241088

Similar Items