Low expression of APAF-1XL in acute myeloid leukemia may be associated with the failure of remission induction therapy

Low expression of APAF-1XL in acute myeloid leukemia may be associated with the failure of remission induction therapy

Apoptotic protease activating factor 1 (APAF-1) has a critical role in the regulation of apoptosis. In the present study, the mRNA expression analysis of different APAF-1 transcripts (APAF-1S, APAF-1LC, APAF-1LN, and APAF-1XL) was analyzed in bone marrow samples from 37 patients with acute myeloid l...

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Bibliographic Details
Main Authors:	B.D. Benites, A. Fattori, C. Hackel, I. Lorand-Metze, C.A. De Souza, E. Schulz, F.F. Costa, S.T.O. Saad
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2008-07-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	APAF-1 Acute myeloid leukemia Apoptosis Chemotherapy resistance
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2008000700004

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