The transformation of sanogenetic and pathogenetic relations after operative treatment of duodenal ulcers

• Main Authors: G. K. Zherlov, N. V. Ryazantseva, S. P. Savchenko
• Format: Article
• Language: English
• Published: Siberian State Medical University (Tomsk) 2005-12-01
• Series: Bûlleten' Sibirskoj Mediciny
• Subjects: duodenal ulcer; pathogenesis; sanogenesis; gastroduodenal complex; gastroduodenoanastomosis; quality of life
• Online Access: https://bulletin.tomsk.ru/jour/article/view/3691

Complex study of secretory and motor-evacuation functions of gastroduodenal complex, of adaptive capabilities of the organism in patients having duodenal ulcers in the follow-up period after various modifications of distal resection of stomach based upon Billroth-I was performed. It was revealed that after pylorus-modelling surgeries, compensatory change of secretory and motor-evacuation functions of the gastroduodenal complex takes place: decrease of acid and pepsin production, normalization of bicarbonate production and mucous sensibility of gastroduodenal complex to regulative effects, reconstruction of receptive relaxation similarity in proximal departments of the stomach during food intake, increase of peristaltic activity during food expulsion; high quality of life is achieved. The forming artificial pylorus plays the leading role in the transformation of pathogenetic and sanogenetic interelations.