Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma.

During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1tm1Fbg (Lpd-/-) was documented. Upon further investigation, the Lpd-/- colony was found to be infected with mult...

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Bibliographic Details
Main Authors: Cassandra L Miller, Sureshkumar Muthupalani, Zeli Shen, Frauke Drees, Zhongming Ge, Yan Feng, Xiaowei Chen, Guanyu Gong, Karan K Nagar, Timothy C Wang, Frank B Gertler, James G Fox
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4821566?pdf=render