TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma

TGF-β Determines the Pro-migratory Potential of bFGF Signaling in Medulloblastoma

Summary: The microenvironment shapes cell behavior and determines metastatic outcomes of tumors. We addressed how microenvironmental cues control tumor cell invasion in pediatric medulloblastoma (MB). We show that bFGF promotes MB tumor cell invasion through FGF receptor (FGFR) in vitro and that blo...

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Bibliographic Details
Main Authors: Karthiga Santhana Kumar, Anuja Neve, Ana S. Guerreiro Stucklin, Claudia M. Kuzan-Fischer, Elisabeth J. Rushing, Michael D. Taylor, Dimitra Tripolitsioti, Lena Behrmann, Daniel Kirschenbaum, Michael A. Grotzer, Martin Baumgartner
Format: Article
Language:English
Published: Elsevier 2018-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718308647

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