DMRfinder: efficiently identifying differentially methylated regions from MethylC-seq data
Abstract Background DNA methylation is an epigenetic modification that is studied at a single-base resolution with bisulfite treatment followed by high-throughput sequencing. After alignment of the sequence reads to a reference genome, methylation counts are analyzed to determine genomic regions tha...
Main Authors: | John M. Gaspar, Ronald P. Hart |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-11-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-017-1909-0 |
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