Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes

Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes

Background: Although toll-like receptor 3 (TLR3) signaling is involved in the development of certain chronic kidney diseases, the specific molecular mechanisms underlying inflammatory reactions via activation of TLR3 signaling in human podocytes remain unclear. Interleukin (IL)-6 is a pleiotropic cy...

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Bibliographic Details
Main Authors: Hidenori Umetsu, Shojiro Watanabe, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
Format: Article
Language:English
Published: Karger Publishers 2021-04-01
Series:Kidney & Blood Pressure Research
Subjects:
c-c motif chemokine ligand 5
interleukin-6
monocyte chemoattractant protein-1
podocytes
toll-like receptor 3
Online Access:https://www.karger.com/Article/FullText/514589

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