Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis.

Analysis of novel NEFL mRNA targeting microRNAs in amyotrophic lateral sclerosis.

Amyotrophic lateral sclerosis (ALS) is a fatal disease characterized by progressive motor neuron degeneration and neurofilament aggregate formation. Spinal motor neurons in ALS also show a selective suppression in the levels of low molecular weight neurofilament (NEFL) mRNA. We have been interested...

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Bibliographic Details
Main Authors: Muhammad Ishtiaq, Danae Campos-Melo, Kathryn Volkening, Michael J Strong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3893244?pdf=render

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