Angiostatin prevents IL-1β-induced down-regulation of eNOS expression by inhibiting the NF-κB cascade

Angiostatin prevents IL-1β-induced down-regulation of eNOS expression by inhibiting the NF-κB cascade

This study aimed to elucidate the protective potential of angiostatin in inflamed endothelial cells in culture. We assessed the effect of angiostatin on the expression of ICAM-1 and eNOS. Angiostatin prevented IL-1β-induced down-regulation of eNOS expression, but produced no significant changes on I...

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Bibliographic Details
Main Authors: Yasushi Kawasaki, Eriko Yokobayashi, Kentaro Sakamoto, Eri Tenma, Haruka Takaki, Yuki Chiba, Tomomi Otashiro, Mai Ishihara, Sei Yonezawa, Akinori Sugiyama, Yasuhiro Natori
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Journal of Pharmacological Sciences
Subjects:
Angiostatin
Anti-inflammatory
Endothelial nitric oxide synthase (eNOS)
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861315002054

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http://www.sciencedirect.com/science/article/pii/S1347861315002054

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