Genetic rodent models of obesity-associated ovarian dysfunction and subfertility: insights into polycystic ovary syndrome

Genetic rodent models of obesity-associated ovarian dysfunction and subfertility: insights into polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is the most common endocrinopathy affecting women, and a leading cause of female infertility worldwide. Defined clinically by the presence of hyperandrogenemia and oligomenorrhoea, PCOS represents a state of hormonal dysregulation, disrupted ovarian follicle dynamics...

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Bibliographic Details
Main Authors: Isabel eHuang-Doran, Stephen eFranks
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-06-01
Series:Frontiers in Endocrinology
Subjects:
Fertility
Insulin Resistance
Obesity
mouse models
androgen
pcos
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00053/full

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