Increased polyamines alter chromatin and stabilize autoantigens in autoimmune diseases

Polyamines are small cations with unique combinations of charge and length that give them many putative interactions in cells. Polyamines are essential since they are involved in replication, transcription, translation, and stabilization of macro-molecular complexes. However, polyamine synthesis com...

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Bibliographic Details
Main Author: Wesley H. Brooks
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00091/full