TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children.

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children.

TNF-α and IFN-γ play a role in the development of mucosal damage in celiac disease (CD). Polymorphisms of TNFA and IFNG genes, as well as of the TNFRSF1A gene, encoding the TNF-α receptor 1, might underlie different inter-individual disease susceptibility over a common HLA risk background. The aims...

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Bibliographic Details
Main Authors: Elisa Rossi, Daniela Basso, Carlo-Federico Zambon, Filippo Navaglia, Eliana Greco, Michela Pelloso, Serena Artuso, Andrea Padoan, Matilde Pescarin, Ada Aita, Dania Bozzato, Stefania Moz, Mara Cananzi, Graziella Guariso, Mario Plebani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4411089?pdf=render

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