PKCζ interacts with STAT3 and promotes its activation in cardiomyocyte hypertrophy

PKCζ interacts with STAT3 and promotes its activation in cardiomyocyte hypertrophy

This study was aimed to investigate the crosstalk between protein kinase C ζ (PKCζ) and signal transducer and activator of transcription 3 (STAT3) in cardiomyocyte hypertrophy. In neonatal rat cardiomyocyte hypertrophic model induced by phenylephrine (PE), the levels of phosphorylated PKCζ and phosp...

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Bibliographic Details
Main Authors: Jingyan Li, Hui Gao, Junying Huang, Panxia Wang, Yi Huang, Wenwei Luo, Xiaoying Zhang, Peiye Shen, Jia You, Sidong Cai, Zhuoming Li, Peiqing Liu
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Journal of Pharmacological Sciences
Subjects:
Cardiac hypertrophy
Phenylephrine
PKCζ
STAT3
Phosphorylation
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861316300044

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