Opposing effects of dopamine antagonism in a motor sequence task - tiapride increases cortical excitability and impairs motor learning

Opposing effects of dopamine antagonism in a motor sequence task - tiapride increases cortical excitability and impairs motor learning

The dopaminergic system is involved in learning and participates in the modulation of cortical excitability (CE). CE has been suggested as a marker of learning and use-dependent plasticity. However, results from separate studies on either motor CE or motor learning challenge this notion, suggesting...

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Bibliographic Details
Main Authors: Silke eLissek, Guido S. Vallana, Lara eSchlaffke, Melanie eLenz, Hubert R Dinse, Martin eTegenthoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Dopamine
fMRI
motor learning
TMS
cortical excitability
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00201/full

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