Age-Dependent Changes in Transcription Factor FOXO Targeting in Female Drosophila

Age-Dependent Changes in Transcription Factor FOXO Targeting in Female Drosophila

FOXO transcription factors have long been associated with longevity control and tissue homeostasis. Although the transcriptional regulation of FOXO have been previously characterized (especially in long-lived insulin mutants and under stress conditions), how normal aging impacts the transcriptional...

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Bibliographic Details
Main Authors: Allison Birnbaum, Xiaofen Wu, Marc Tatar, Nan Liu, Hua Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Genetics
Subjects:
forkhead transcription factor FOXO
ChIP-Seq
transcriptional regulation
longevity control
insulin
hippo
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00312/full

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https://www.frontiersin.org/article/10.3389/fgene.2019.00312/full

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