Influence of wild-type <it>MLL </it>on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia

Influence of wild-type <it>MLL </it>on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia

<p>Abstract</p> <p>Background</p> <p>Rearrangement of the mixed-lineage leukemia gene (<it>MLL</it>) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and resistance to glucocorticoids (GCs). We have recently...

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Bibliographic Details
Main Authors: Firth Martin J, Samuels Amy L, Heng Jasmin YS, Palmer Misty-Lee, Rampellini Janelle L, Beesley Alex H, Ford Jette, Kees Ursula R
Format: Article
Language:English
Published: BMC 2010-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/284

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