Influence of wild-type <it>MLL </it>on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia
<p>Abstract</p> <p>Background</p> <p>Rearrangement of the mixed-lineage leukemia gene (<it>MLL</it>) is found in 80% of infant acute lymphoblastic leukemia (ALL) and is associated with poor prognosis and resistance to glucocorticoids (GCs). We have recently...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2010-10-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/9/1/284 |