Whole exome sequencing reveals the different responsiveness to Enterovirus 71 vaccination in Chinese children

Whole exome sequencing reveals the different responsiveness to Enterovirus 71 vaccination in Chinese children

Purpose: To explore the molecular genetic mechanisms underlying different responsiveness to Enterovirus 71 (EV71) vaccine. Methods: We recruited 10,245 healthy children into a phase 3 clinical trial to evaluate the efficacy of EV71 vaccine in 2012. Fifty subjects from the trial were divided into the...

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Bibliographic Details
Main Authors:	Li Zhang, Chengxiao Yu, Zijun Ge, Hong Tao, Fanyue Meng, Xin Xu, Ting Tian, Ci Song, Zhibin Hu, Jingxin Li, Fengcai Zhu
Format:	Article
Language:	English
Published:	Elsevier 2020-08-01
Series:	International Journal of Infectious Diseases
Subjects:	WES Different immune responsiveness EV71 vaccine
Online Access:	http://www.sciencedirect.com/science/article/pii/S1201971220304434

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