Downregulation of Src Family Kinase Activity Using PP2 Inhibitor Has No Effect on the Elongation of Pragmin-Transfected Adenocarcinoma AGS cells

Downregulation of Src Family Kinase Activity Using PP2 Inhibitor Has No Effect on the Elongation of Pragmin-Transfected Adenocarcinoma AGS cells

Introduction: Pragmin is the first mammalian protein that contains a functional the Glu-ProIle-Tyr-Ala (EPIYA) motif. Pragmin is tyrosine-phosphorylated at EPIYA motif by Src family kinases (SFKs), C-terminal Src kinase (CSK), and in response to epidermal growth factor (EGF) stimulation. Pragmin can...

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Bibliographic Details
Main Authors: Fatemeh Safari, Sheida Jodayri Zayer
Format: Article
Language:English
Published: Zabol University of Medical sciences 2018-03-01
Series:International Journal of Basic Science in Medicine
Subjects:
Pragmin
Morphological changes
EPIYA motif
Src
PP2 inhibitor
Adenocarcinoma
Online Access:http://ijbsm.zbmu.ac.ir/PDF/ijbsm-3213

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