Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage

Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage

Abstract Background Metastatic castration-resistant prostate cancer (CRPC) is the leading cause of death among men diagnosed with prostate cancer. Piperlongumine (PL) is a novel potential anticancer agent that has been demonstrated to exhibit anticancer efficacy against prostate cancer cells. Howeve...

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Bibliographic Details
Main Authors: Ding-fang Zhang, Zhi-chun Yang, Jian-qiang Chen, Xiang-xiang Jin, Yin-da Qiu, Xiao-jing Chen, Hong-yi Shi, Zhi-guo Liu, Min-shan Wang, Guang Liang, Xiao-hui Zheng
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Castration-resistant prostate cancer
Piperlongumine
Cancer migration
DNA damage
DNA repair
DNA damage response
Online Access:https://doi.org/10.1186/s12906-021-03369-0

Internet

https://doi.org/10.1186/s12906-021-03369-0

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