Perspectives for diagnostic and treatment in alcoholic encephalopathy at early disease stage

• Main Authors: E. R. Barantsevich, K. G. Kurashevich
• Format: Article
• Language: Russian
• Published: Academician I.P. Pavlov First St. Petersburg State Medical University 2015-12-01
• Series: Učenye Zapiski Sankt-Peterburgskogo Gosudarstvennogo Medicinskogo Universiteta im. Akad. I.P. Pavlova
• Subjects: алкогольная энцефалопатия; нейромидин; метадоксил; alcoholic encephalopathy; neiromidin; metadoxil
• Online Access: https://www.sci-notes.ru/jour/article/view/162

101 patients with alcoholic encephalopathy, aged from 30 to 60 years, were enrolled in the study. Patients were divided into three groups: 34 patients in the treatment group received neiromidin in a dose of 15 mg in solution during 10 days and then in tabs in a dose of 20 mg three times a day during 2 months; 32 patients in the treatment group received vasoactive, antioxidant treatment and metadoxil in a dose of 500 mg three times a day during 2 months. The comparison group included 35 patients receiving only vasoactive and antioxidant treatment. To the end of treatment, the positive changes in the state of patients reflected in the decrease in the number of complaints and neurological symptoms were seen in the treatment groups.