Modern Myoma Treatment in the Last 20 Years: A Review of the Literature

Myomas, also known as fibroids, are a specific characteristic of the human species. No other primates develop fibroids. At a cellular level, myomas are benign hyperplastic lesions of uterine smooth muscle cells. There are interesting theoretical concepts that link the development of myomas in humans...

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Main Authors: Ahmed El-Balat, Rudy Leon DeWilde, Iryna Schmeil, Morva Tahmasbi-Rad, Sandra Bogdanyova, Ali Fathi, Sven Becker
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/4593875
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spelling doaj-aca88a745ee54a1793a75be3f93fc3012020-11-25T00:23:24ZengHindawi LimitedBioMed Research International2314-61332314-61412018-01-01201810.1155/2018/45938754593875Modern Myoma Treatment in the Last 20 Years: A Review of the LiteratureAhmed El-Balat0Rudy Leon DeWilde1Iryna Schmeil2Morva Tahmasbi-Rad3Sandra Bogdanyova4Ali Fathi5Sven Becker6Department of Gynecology and Obstetrics, Goethe-University, Frankfurt, GermanyClinic of Gynecology, Obstetrics and Gynecological Oncology, Pius Hospital, University Hospital for Gynecology, Carl von Ossietzky University Medical School, Oldenburg, GermanyDepartment of Gynecology and Obstetrics, Goethe-University, Frankfurt, GermanyDepartment of Gynecology and Obstetrics, Goethe-University, Frankfurt, GermanyDepartment of Gynecology and Obstetrics, Goethe-University, Frankfurt, GermanyDepartment of Gynecology and Obstetrics, Goethe-University, Frankfurt, GermanyDepartment of Gynecology and Obstetrics, Goethe-University, Frankfurt, GermanyMyomas, also known as fibroids, are a specific characteristic of the human species. No other primates develop fibroids. At a cellular level, myomas are benign hyperplastic lesions of uterine smooth muscle cells. There are interesting theoretical concepts that link the development of myomas in humans with the highly specific process of childbirth from an upright position and the resulting need for greatly increased “expulsive” forces during labor. Myomas might be the price our species pays for our bipedal and highly intelligent existence. Myomas affect, with some variability, all ethnic groups and approximately 50% of all women during their lifetime. While some remain asymptomatic, myomas can cause significant and sometimes life-threatening uterine bleeding, pain, infertility, and, in extreme cases, ureteral obstruction and death. Traditionally, over 50% of all hysterectomies were performed for fibroids, leading to a significant healthcare burden. In this article, we review the developments of the past 20 years with regard to multiple new treatment strategies that have evolved during this time.http://dx.doi.org/10.1155/2018/4593875
collection DOAJ
language English
format Article
sources DOAJ
author Ahmed El-Balat
Rudy Leon DeWilde
Iryna Schmeil
Morva Tahmasbi-Rad
Sandra Bogdanyova
Ali Fathi
Sven Becker
spellingShingle Ahmed El-Balat
Rudy Leon DeWilde
Iryna Schmeil
Morva Tahmasbi-Rad
Sandra Bogdanyova
Ali Fathi
Sven Becker
Modern Myoma Treatment in the Last 20 Years: A Review of the Literature
BioMed Research International
author_facet Ahmed El-Balat
Rudy Leon DeWilde
Iryna Schmeil
Morva Tahmasbi-Rad
Sandra Bogdanyova
Ali Fathi
Sven Becker
author_sort Ahmed El-Balat
title Modern Myoma Treatment in the Last 20 Years: A Review of the Literature
title_short Modern Myoma Treatment in the Last 20 Years: A Review of the Literature
title_full Modern Myoma Treatment in the Last 20 Years: A Review of the Literature
title_fullStr Modern Myoma Treatment in the Last 20 Years: A Review of the Literature
title_full_unstemmed Modern Myoma Treatment in the Last 20 Years: A Review of the Literature
title_sort modern myoma treatment in the last 20 years: a review of the literature
publisher Hindawi Limited
series BioMed Research International
issn 2314-6133
2314-6141
publishDate 2018-01-01
description Myomas, also known as fibroids, are a specific characteristic of the human species. No other primates develop fibroids. At a cellular level, myomas are benign hyperplastic lesions of uterine smooth muscle cells. There are interesting theoretical concepts that link the development of myomas in humans with the highly specific process of childbirth from an upright position and the resulting need for greatly increased “expulsive” forces during labor. Myomas might be the price our species pays for our bipedal and highly intelligent existence. Myomas affect, with some variability, all ethnic groups and approximately 50% of all women during their lifetime. While some remain asymptomatic, myomas can cause significant and sometimes life-threatening uterine bleeding, pain, infertility, and, in extreme cases, ureteral obstruction and death. Traditionally, over 50% of all hysterectomies were performed for fibroids, leading to a significant healthcare burden. In this article, we review the developments of the past 20 years with regard to multiple new treatment strategies that have evolved during this time.
url http://dx.doi.org/10.1155/2018/4593875
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