Rapport sur la Meningite Cerebrospinale Epidemique a Teheran

Thirty cases have been studied in the recent epidemic of meningococcal meningitis. In fourteen of these cases organisms were isolated."nIn all these the organisms were proved to be meningococcus type A; with following characteristics:"n1-Different culture media were tried; blood ag...

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Main Authors:	A. Machhoun, H. Siadat
Format:	Article
Language:	English
Published:	Tehran University of Medical Sciences 1958-01-01
Series:	Acta Medica Iranica
Online Access:	http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/11506.pdf&manuscript_id=11506

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spelling	doaj-ac9b35bbff9c4a7781865a0ad0f44f912020-11-25T03:49:35ZengTehran University of Medical SciencesActa Medica Iranica0044-60251958-01-012119Rapport sur la Meningite Cerebrospinale Epidemique a TeheranA. MachhounH. SiadatThirty cases have been studied in the recent epidemic of meningococcal meningitis. In fourteen of these cases organisms were isolated."nIn all these the organisms were proved to be meningococcus type A; with following characteristics:"n1-Different culture media were tried; blood agar was found to be the best.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 2-One week after the onset of the illness, serum test was tried with the patient's sera and meningococci type A. All were positive (1/160-1/640). The reaction was negative with the organisms of types B, C and also with the sera of patients suffering from lymphocytic meningitis.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 3-Crossed agglutination was positive with the serum obtained from each patient; and the organisms isolated from the other; thus"nprov ing the common origin of the epidemic. 4-In most of the cases seroprecipitation from centrifugated C.S.F. with antimeningococcal A serum was positive. 5-All the strains obtained were highly sensitive to sulphonamides, The sensitivity to penicillin, erythromycin, oleandomycin and chloramphenicol was fairly good; but to other antibiotics it was less marked. 6-This sensitivity to sulfonamides has not deterioted up to this date, and we have not found any strain resistent to this drug. 7-The clinical pattern of the disease has somewhat changed during the course of the epidemic. At first classical types were more often seen, hut later the cases admitted were more severe, with Coma and convulsionhttp://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/11506.pdf&manuscript_id=11506
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	A. Machhoun H. Siadat
spellingShingle	A. Machhoun H. Siadat Rapport sur la Meningite Cerebrospinale Epidemique a Teheran Acta Medica Iranica
author_facet	A. Machhoun H. Siadat
author_sort	A. Machhoun
title	Rapport sur la Meningite Cerebrospinale Epidemique a Teheran
title_short	Rapport sur la Meningite Cerebrospinale Epidemique a Teheran
title_full	Rapport sur la Meningite Cerebrospinale Epidemique a Teheran
title_fullStr	Rapport sur la Meningite Cerebrospinale Epidemique a Teheran
title_full_unstemmed	Rapport sur la Meningite Cerebrospinale Epidemique a Teheran
title_sort	rapport sur la meningite cerebrospinale epidemique a teheran
publisher	Tehran University of Medical Sciences
series	Acta Medica Iranica
issn	0044-6025
publishDate	1958-01-01
description	Thirty cases have been studied in the recent epidemic of meningococcal meningitis. In fourteen of these cases organisms were isolated."nIn all these the organisms were proved to be meningococcus type A; with following characteristics:"n1-Different culture media were tried; blood agar was found to be the best.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 2-One week after the onset of the illness, serum test was tried with the patient's sera and meningococci type A. All were positive (1/160-1/640). The reaction was negative with the organisms of types B, C and also with the sera of patients suffering from lymphocytic meningitis.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; 3-Crossed agglutination was positive with the serum obtained from each patient; and the organisms isolated from the other; thus"nprov ing the common origin of the epidemic. 4-In most of the cases seroprecipitation from centrifugated C.S.F. with antimeningococcal A serum was positive. 5-All the strains obtained were highly sensitive to sulphonamides, The sensitivity to penicillin, erythromycin, oleandomycin and chloramphenicol was fairly good; but to other antibiotics it was less marked. 6-This sensitivity to sulfonamides has not deterioted up to this date, and we have not found any strain resistent to this drug. 7-The clinical pattern of the disease has somewhat changed during the course of the epidemic. At first classical types were more often seen, hut later the cases admitted were more severe, with Coma and convulsion
url	http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/11506.pdf&manuscript_id=11506
work_keys_str_mv	AT amachhoun rapportsurlameningitecerebrospinaleepidemiqueateheran AT hsiadat rapportsurlameningitecerebrospinaleepidemiqueateheran
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Rapport sur la Meningite Cerebrospinale Epidemique a Teheran

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