New <sup>55</sup>Co-labeled Albumin-Binding Folate Derivatives as Potential PET Agents for Folate Receptor Imaging

New <sup>55</sup>Co-labeled Albumin-Binding Folate Derivatives as Potential PET Agents for Folate Receptor Imaging

Overexpression of folate receptors (FRs) on different tumor types (e.g., ovarian, lung) make FRs attractive in vivo targets for directed diagnostic/therapeutic agents. Currently, no diagnostic agent suitable for positron emission tomography (PET) has been adopted for clinical FR imaging. In this wor...

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Bibliographic Details
Main Authors: Lauren L. Radford, Solana Fernandez, Rebecca Beacham, Retta El Sayed, Renata Farkas, Martina Benešová, Cristina Müller, Suzanne E. Lapi
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Pharmaceuticals
Subjects:
folic acid
folate receptors
cobalt-55
pet imaging
albumin binder
ovarian cancer
Online Access:https://www.mdpi.com/1424-8247/12/4/166

Internet

https://www.mdpi.com/1424-8247/12/4/166

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