Lithium Ameliorates LPS-Induced Astrocytes Activation Partly via Inhibition of Toll-Like Receptor 4 Expression

Lithium Ameliorates LPS-Induced Astrocytes Activation Partly via Inhibition of Toll-Like Receptor 4 Expression

Background/Aims: Astrocytes are critical for the development of postoperative cognitive dysfunction (POCD). In addition, astrocytes express toll-like receptors 4 (TLR4) and build up responses to innate immune triggers by releasing pro-inflammatory molecules. The pathogenesis of neurological disorder...

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Bibliographic Details
Main Authors: Nana Li, Xiang Zhang, Hongquan Dong, Susu Zhang, Jie Sun, Yanning Qian
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
POCD
Astrocytes
Lithium
TLR4
Online Access:http://www.karger.com/Article/FullText/443028

Internet

http://www.karger.com/Article/FullText/443028

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