Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance

Differential mRNA expression of the main apoptotic proteins in normal and malignant cells and its relation to in vitro resistance

Abstract Background Apoptosis plays an important role in the development and homeostasis of multicellular organisms and its deregulation may result in many serious diseases, including cancer. Now it is clear that some oncogenic mutations disrupt apoptosis, leading to tumour initiation, progression o...

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Bibliographic Details
Main Authors: Andrea Vazanova, Jana Jurecekova, Tomas Balharek, Juraj Marcinek, Jan Stasko, Anton Dzian, Lukas Plank, Pavol Zubor, Peter Racay, Jozef Hatok
Format: Article
Language:English
Published: BMC 2018-03-01
Series:Cancer Cell International
Subjects:
Apoptosis
Resistance
Malignant cells
mRNA expression
Online Access:http://link.springer.com/article/10.1186/s12935-018-0528-9

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http://link.springer.com/article/10.1186/s12935-018-0528-9

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