Whole Brain Radiotherapy and RRx-001: Two Partial Responses in Radioresistant Melanoma Brain Metastases from a Phase I/II Clinical Trial

Whole Brain Radiotherapy and RRx-001: Two Partial Responses in Radioresistant Melanoma Brain Metastases from a Phase I/II Clinical Trial

BACKGROUND: Kim et al. report two patients with melanoma metastases to the brain that responded to treatment with RRx-001 and whole brain radiotherapy (WBRT) without neurologic or systemic toxicity in the context of a phase I/II clinical trial. RRx-001 is an reactive oxygen and reactive nitrogen spe...

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Bibliographic Details
Main Authors: Michelle M. Kim, Hemant Parmar, Yue Cao, Priyanka Pramanik, Matthew Schipper, James Hayman, Larry Junck, Aaron Mammoser, Jason Heth, Corey A. Carter, Arnold Oronsky, Susan J. Knox, Scott Caroen, Bryan Oronsky, Jan Scicinski, Theodore S. Lawrence, Christopher D. Lao
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523315300668

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http://www.sciencedirect.com/science/article/pii/S1936523315300668

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