Detection of 22 common leukemic fusion genes using a single-step multiplex qRT-PCR-based assay

Detection of 22 common leukemic fusion genes using a single-step multiplex qRT-PCR-based assay

Abstract Background Fusion genes generated from chromosomal translocation play an important role in hematological malignancies. Detection of fusion genes currently employ use of either conventional RT-PCR methods or fluorescent in situ hybridization (FISH), where both methods involve tedious methodo...

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Bibliographic Details
Main Authors: Xiaodong Lyu, Xianwei Wang, Lina Zhang, Zhenzhu Chen, Yu Zhao, Jieying Hu, Ruihua Fan, Yongping Song
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Diagnostic Pathology
Subjects:
Leukemia
F-qRT-PCR
AML
MDS
CLL
ALL
Online Access:http://link.springer.com/article/10.1186/s13000-017-0634-3

Internet

http://link.springer.com/article/10.1186/s13000-017-0634-3

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