Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates

Respiratory and intestinal epithelial cells exhibit differential susceptibility and innate immune responses to contemporary EV-D68 isolates

Enterovirus D68 (EV-D68) has been implicated in outbreaks of severe respiratory illness and is associated with acute flaccid myelitis (AFM). EV-D68 is often detected in patient respiratory samples but has also been detected in stool and wastewater, suggesting the potential for both respiratory and e...

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Bibliographic Details
Main Authors: Megan Culler Freeman, Alexandra I Wells, Jessica Ciomperlik-Patton, Michael M Myerburg, Liheng Yang, Jennifer Konopka-Anstadt, Carolyn B Coyne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-07-01
Series:eLife
Subjects:
enterovirus
airway
intestine
interferon
Online Access:https://elifesciences.org/articles/66687

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