Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer

Given the serious threat of lung cancer due to the strong concealment at early stage, primary diagnosis becomes quite essential to guarantee human health. The adsorption behaviors of introduced Ir-CNT upon two categories of typical gases of lung cancer (aniline and o-toluidine) have been investigate...

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Main Authors: Qianqian Wan, Yancheng Xu, Hanyan Xiao
Format: Article
Language:English
Published: AIP Publishing LLC 2018-10-01
Series:AIP Advances
Online Access:http://dx.doi.org/10.1063/1.5050435
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spelling doaj-ac6c8688a9e14c23901df62d05b4c7d92020-11-25T02:27:32ZengAIP Publishing LLCAIP Advances2158-32262018-10-01810105128105128-1010.1063/1.5050435101810ADVExhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancerQianqian Wan0Yancheng Xu1Hanyan Xiao2Zhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, ChinaZhongnan Hospital of Wuhan University, Wuhan, Hubei 430071, ChinaSchool of Electrical Engineering, Chongqing University, Chongqing 400044, ChinaGiven the serious threat of lung cancer due to the strong concealment at early stage, primary diagnosis becomes quite essential to guarantee human health. The adsorption behaviors of introduced Ir-CNT upon two categories of typical gases of lung cancer (aniline and o-toluidine) have been investigated based on DFT method. At the same time, the sensing characteristics towards these two gases were conducted as well by our prepared sensors prepared by drying the Ir deposited CNT aqueous solution onto the interdigital electrode substrate. Results indicate that Ir-CNT based material can be desirable and promising for sensing upon exhaled gas of lung cancer patient, because of the excellent adsorptions upon two kinds of main typical gases. Such strong interactions of Ir-CNT towards typical gas adsorbed leads to the significant electronic redistributions of the modified surface, thereby causing apparent reduction in conductivity after adsorptions. This could be detected by a practical prepared resistivity-type sensor. Our theoretical calculations are in good accordance with the experimental results, which demonstrate the feasibility of Ir-CNT for potential application in the near future in the field of lung cancer diagnosis.http://dx.doi.org/10.1063/1.5050435
collection DOAJ
language English
format Article
sources DOAJ
author Qianqian Wan
Yancheng Xu
Hanyan Xiao
spellingShingle Qianqian Wan
Yancheng Xu
Hanyan Xiao
Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer
AIP Advances
author_facet Qianqian Wan
Yancheng Xu
Hanyan Xiao
author_sort Qianqian Wan
title Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer
title_short Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer
title_full Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer
title_fullStr Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer
title_full_unstemmed Exhaled gas detection by Ir-doped CNT for primary diagnosis of lung cancer
title_sort exhaled gas detection by ir-doped cnt for primary diagnosis of lung cancer
publisher AIP Publishing LLC
series AIP Advances
issn 2158-3226
publishDate 2018-10-01
description Given the serious threat of lung cancer due to the strong concealment at early stage, primary diagnosis becomes quite essential to guarantee human health. The adsorption behaviors of introduced Ir-CNT upon two categories of typical gases of lung cancer (aniline and o-toluidine) have been investigated based on DFT method. At the same time, the sensing characteristics towards these two gases were conducted as well by our prepared sensors prepared by drying the Ir deposited CNT aqueous solution onto the interdigital electrode substrate. Results indicate that Ir-CNT based material can be desirable and promising for sensing upon exhaled gas of lung cancer patient, because of the excellent adsorptions upon two kinds of main typical gases. Such strong interactions of Ir-CNT towards typical gas adsorbed leads to the significant electronic redistributions of the modified surface, thereby causing apparent reduction in conductivity after adsorptions. This could be detected by a practical prepared resistivity-type sensor. Our theoretical calculations are in good accordance with the experimental results, which demonstrate the feasibility of Ir-CNT for potential application in the near future in the field of lung cancer diagnosis.
url http://dx.doi.org/10.1063/1.5050435
work_keys_str_mv AT qianqianwan exhaledgasdetectionbyirdopedcntforprimarydiagnosisoflungcancer
AT yanchengxu exhaledgasdetectionbyirdopedcntforprimarydiagnosisoflungcancer
AT hanyanxiao exhaledgasdetectionbyirdopedcntforprimarydiagnosisoflungcancer
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