A novel role for the GTPase-activating protein Bud2 in the spindle position checkpoint.

The spindle position checkpoint (SPC) ensures correct mitotic spindle position before allowing mitotic exit in the budding yeast Saccharomyces cerevisiae. In a candidate screen for checkpoint genes, we identified bud2Δ as deficient for the SPC. Bud2 is a GTPase activating protein (GAP), and the only...

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Bibliographic Details
Main Authors: Scott A Nelson, Anthony M Sanson, Hay-Oak Park, John A Cooper
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338500?pdf=render