Therapeutic effect of integrin-linked kinase gene-modified bone marrow-derived mesenchymal stem cells for streptozotocin-induced diabetic cystopathy in a rat model

Therapeutic effect of integrin-linked kinase gene-modified bone marrow-derived mesenchymal stem cells for streptozotocin-induced diabetic cystopathy in a rat model

Abstract Background Diabetic cystopathy (DCP) is a chronic complication of diabetes mainly within the submucosal and muscular layers of the bladder due to the hyperglycemia-induced ischemia. As no effective therapies are currently available, the administration of optimized mesenchymal stem cells (MS...

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Bibliographic Details
Main Authors: Yi Huang, Jie Gao, Yiduo Zhou, Shuo Wu, Yunpeng Shao, Haoliang Xue, Baixin Shen, Liucheng Ding, Zhongqing Wei
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Bone marrow-derived mesenchymal stem cells
Diabetic cystopathy
Integrin-linked kinase
Angiogenesis
Proliferation
Antiapoptosis
Online Access:http://link.springer.com/article/10.1186/s13287-020-01795-4

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http://link.springer.com/article/10.1186/s13287-020-01795-4

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