Exploiting Sparse Statistics for a Sequence-Based Prediction of the Effect of Mutations
Recent work showed that there is a significant difference between the statistics of amino acid triplets and quadruplets in sequences of folded proteins and randomly generated sequences. These statistics were used to assign a score to each sequence and make a prediction whether a sequence is likely t...
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Format: | Article |
Language: | English |
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MDPI AG
2019-10-01
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Series: | Algorithms |
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Online Access: | https://www.mdpi.com/1999-4893/12/10/214 |