Exploiting Sparse Statistics for a Sequence-Based Prediction of the Effect of Mutations

Recent work showed that there is a significant difference between the statistics of amino acid triplets and quadruplets in sequences of folded proteins and randomly generated sequences. These statistics were used to assign a score to each sequence and make a prediction whether a sequence is likely t...

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Bibliographic Details
Main Author: Mihaly Mezei
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Algorithms
Subjects:
Online Access:https://www.mdpi.com/1999-4893/12/10/214