Development of a Method for the Quantification of Clotrimazole and Itraconazole and Study of Their Stability in a New Microemulsion for the Treatment of Sporotrichosis

Development of a Method for the Quantification of Clotrimazole and Itraconazole and Study of Their Stability in a New Microemulsion for the Treatment of Sporotrichosis

Sporotrichosis occurs worldwide and is caused by the fungus <i>Sporothrix brasiliensis</i>. This agent has a high zoonotic potential and is transmitted mainly by bites and scratches from infected felines. A new association between the drugs clotrimazole and itraconazole is shown to be ef...

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Bibliographic Details
Main Authors: Patricia Garcia Ferreira, Carolina Guimarães de Souza Lima, Letícia Lorena Noronha, Marcela Cristina de Moraes, Fernando de Carvalho da Silva, Alessandra Lifsitch Viçosa, Débora Omena Futuro, Vitor Francisco Ferreira
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Molecules
Subjects:
pre-development process
clotrimazole
itraconazole
stability
method validation
sporotrichosis
Online Access:https://www.mdpi.com/1420-3049/24/12/2333

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