Sensitive real-time PCR detection of pathogenic Leptospira spp. and a comparison of nucleic acid amplification methods for the diagnosis of leptospirosis.

Sensitive real-time PCR detection of pathogenic Leptospira spp. and a comparison of nucleic acid amplification methods for the diagnosis of leptospirosis.

Bacteria of the genus Leptospira, the causative agents of leptospirosis, are categorized into pathogenic and non-pathogenic species. However, the benefit of using a clinical diagnostic that is specific for pathogenic species remains unclear. In this study, we present the development of a real-time P...

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Bibliographic Details
Main Authors: Jesse J Waggoner, Ilana Balassiano, Janaki Abeynayake, Malaya K Sahoo, Alisha Mohamed-Hadley, Yuanyuan Liu, Juliana Magalhães Vital-Brazil, Benjamin A Pinsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4224423?pdf=render

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