In silico target-specific siRNA design based on domain transfer in heterogeneous data.

In silico target-specific siRNA design based on domain transfer in heterogeneous data.

RNA interference via exogenous small interference RNAs (siRNA) is a powerful tool in gene function study and disease treatment. Designing efficient and specific siRNA on target gene remains the key issue in RNAi. Although various in silico models have been proposed for rational siRNA design, most of...

Full description

Bibliographic Details
Main Authors: Qi Liu, Han Zhou, Kui Zhang, Xiaoxiao Shi, Wei Fan, Ruixin Zhu, Philip S Yu, Zhiwei Cao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23284642/pdf/?tool=EBI

Similar Items

Similar Items