A Non-invasive Digital Biomarker for the Detection of Rest Disturbances in the SOD1G93A Mouse Model of ALS

A Non-invasive Digital Biomarker for the Detection of Rest Disturbances in the SOD1G93A Mouse Model of ALS

Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disease that affects both central and peripheral nervous system, leading to the degeneration of motor neurons, which eventually results in muscle atrophy, paralysis, and death. Sleep disturbances are common in patients with ALS,...

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Bibliographic Details
Main Authors: Elisabetta Golini, Mara Rigamonti, Fabio Iannello, Carla De Rosa, Ferdinando Scavizzi, Marcello Raspa, Silvia Mandillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Neuroscience
Subjects:
ALS
SOD1G93A
sleep
home cage monitoring
DVC®
mouse behavioral phenotyping
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00896/full

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