<i>Cis</i>-Segregation of c.1171C>T Stop Codon (p.R391*) in <i>SERPINC1</i> Gene and c.1691G>A Transition (p.R506Q) in <i>F5</i> Gene and Selected GWAS Multilocus Approach in Inherited Thrombophilia

<i>Cis</i>-Segregation of c.1171C>T Stop Codon (p.R391*) in <i>SERPINC1</i> Gene and c.1691G>A Transition (p.R506Q) in <i>F5</i> Gene and Selected GWAS Multilocus Approach in Inherited Thrombophilia

Inherited thrombophilia (e.g., venous thromboembolism, VTE) is due to rare loss-of-function mutations in anticoagulant factors genes (i.e., <i>SERPINC1</i>, <i>PROC</i>, <i>PROS1</i>), common gain-of-function mutations in procoagulant factors genes (i.e., <i>...

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Bibliographic Details
Main Authors: Donato Gemmati, Giovanna Longo, Eugenia Franchini, Juliana Araujo Silva, Ines Gallo, Barbara Lunghi, Stefano Moratelli, Iva Maestri, Maria Luisa Serino, Veronica Tisato
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
<i>SERPINC1</i>
<i>F5</i>
FV Leiden
GWAS
<i>cis</i>-segregation
crossing-over
Online Access:https://www.mdpi.com/2073-4425/12/6/934

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