Neutralizing-antibody-mediated protection of chickens against infectious bursal disease via one-time vaccination with inactivated recombinant Lactococcus lactis expressing a fusion protein constructed from the RCK protein of Salmonella enterica and VP2 of infectious bursal disease virus

Neutralizing-antibody-mediated protection of chickens against infectious bursal disease via one-time vaccination with inactivated recombinant Lactococcus lactis expressing a fusion protein constructed from the RCK protein of Salmonella enterica and VP2 of infectious bursal disease virus

Abstract Background Infectious bursal disease (IBD) is an acute contagious immunosuppressive disease which lead to acute bursal injury and immune dysfunction in poultry. It has caused heavy economic losses in the commercial poultry industry for many years in worldwide. Attenuated live vaccine has wi...

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Bibliographic Details
Main Authors: Wenqian Wang, Yuxin Song, Linlin Liu, Yuan Zhang, Tingting Wang, Wang Zhang, Kai Li, Xiaole Qi, Yulong Gao, Li Gao, Changjun Liu, Yanping Zhang, Yongqiang Wang, Qing Pan, Gaoming He, Xiaomei Wang, Hongyu Cui
Format: Article
Language:English
Published: BMC 2019-01-01
Series:Microbial Cell Factories
Subjects:
Recombinant lactic acid bacteria
IBDV
RCK
VP2
Online Access:http://link.springer.com/article/10.1186/s12934-019-1061-9

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