Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line.

Epithelial to mesenchymal transition by TGFβ-1 induction increases stemness characteristics in primary non small cell lung cancer cell line.

<h4>Background</h4>Cancer Stem Cells (CSCs) hypothesis asserts that only a small subset of cells within a tumour is capable of both tumour initiation and sustainment. The Epithelial-Mesenchymal Transition (EMT) is an embryonic developmental program that is often activated during cancer i...

Full description

Bibliographic Details
Main Authors: Giuseppe Pirozzi, Virginia Tirino, Rosa Camerlingo, Renato Franco, Aantonello La Rocca, Eleonora Liguori, Nicola Martucci, Francesca Paino, Nicola Normanno, Gaetano Rocco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21738704/pdf/?tool=EBI

Similar Items

Similar Items