Homeostatic proliferation fails to efficiently reactivate HIV-1 latently infected central memory CD4+ T cells.
Homeostatic proliferation ensures the longevity of central memory T-cells by inducing cell proliferation in the absence of cellular differentiation or activation. This process is governed mainly by IL-7. Central memory T-cells can also be stimulated via engagement of the T-cell receptor, leading to...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-10-01
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| Series: | PLoS Pathogens |
| Online Access: | http://europepmc.org/articles/PMC3188522?pdf=render |