Fate and propagation of endogenously formed Tau aggregates in neuronal cells

Abstract Tau accumulation in the form of neurofibrillary tangles in the brain is a hallmark of tauopathies such as Alzheimer's disease (AD). Tau aggregates accumulate in brain regions in a defined spatiotemporal pattern and may induce the aggregation of native Tau in a prion‐like manner. Howeve...

Full description

Bibliographic Details
Main Authors: Patricia Chastagner, Frida Loria, Jessica Y Vargas, Josh Tois, Marc I Diamond, George Okafo, Christel Brou, Chiara Zurzolo
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.202012025