Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.

While it is known that the use of health care resources increases at the end of life in patients admitted to the Intensive Care Unit (ICU), the allocation of blood products at the end of life has not been described. The objective of this study was to describe overall transfusion patterns in the ICU,...

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Main Authors: Nadine Shehata, Alan J Forster, Nadine Lawrence, Robin Ducharme, Dean A Fergusson, Michaël Chassé, Deanna M Rothwell, Paul C Hébert, Alan T Tinmouth, Kumanan Wilson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4575028?pdf=render
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spelling doaj-ac009ce8adf7418ca97e3f917870f86d2020-11-25T00:19:15ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01109e013842710.1371/journal.pone.0138427Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.Nadine ShehataAlan J ForsterNadine LawrenceRobin DucharmeDean A FergussonMichaël ChasséDeanna M RothwellPaul C HébertAlan T TinmouthKumanan WilsonWhile it is known that the use of health care resources increases at the end of life in patients admitted to the Intensive Care Unit (ICU), the allocation of blood products at the end of life has not been described. The objective of this study was to describe overall transfusion patterns in the ICU, and specifically in patients who die in hospital. We conducted a retrospective cohort study of adult patients admitted to the ICU of a university-affiliated hospital, who were discharged or died between November 1, 2006 and June 30, 2012. During the study period, 10,642 patients were admitted at least once to the ICU. Of these patients, 4079 (38.3%) received red blood cells (RBCs), plasma or platelets in the ICU. The ICU mortality rate was 28.1% and in-hospital mortality rate was 32.3%. Among 39,591 blood product units transfused over the course of the study in the ICU (18,144 RBC units, 16,920 plasma units and 4527 platelet units), 46.2% were administered to patients who later died within the same hospitalization (41.2% of RBCs, 50.4% of plasma and 50.8% of platelets). Of all blood product units (RBCs, plasma and platelets) administered in the ICU over the study period, 11% were given within the last 24 hours before death. A large proportion of blood products used in the ICU are administered to patients who ultimately succumb to their illness in hospital, and many of these blood units are given in close proximity to death.http://europepmc.org/articles/PMC4575028?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Nadine Shehata
Alan J Forster
Nadine Lawrence
Robin Ducharme
Dean A Fergusson
Michaël Chassé
Deanna M Rothwell
Paul C Hébert
Alan T Tinmouth
Kumanan Wilson
spellingShingle Nadine Shehata
Alan J Forster
Nadine Lawrence
Robin Ducharme
Dean A Fergusson
Michaël Chassé
Deanna M Rothwell
Paul C Hébert
Alan T Tinmouth
Kumanan Wilson
Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.
PLoS ONE
author_facet Nadine Shehata
Alan J Forster
Nadine Lawrence
Robin Ducharme
Dean A Fergusson
Michaël Chassé
Deanna M Rothwell
Paul C Hébert
Alan T Tinmouth
Kumanan Wilson
author_sort Nadine Shehata
title Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.
title_short Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.
title_full Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.
title_fullStr Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.
title_full_unstemmed Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis.
title_sort transfusion patterns in all patients admitted to the intensive care unit and in those who die in hospital: a descriptive analysis.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2015-01-01
description While it is known that the use of health care resources increases at the end of life in patients admitted to the Intensive Care Unit (ICU), the allocation of blood products at the end of life has not been described. The objective of this study was to describe overall transfusion patterns in the ICU, and specifically in patients who die in hospital. We conducted a retrospective cohort study of adult patients admitted to the ICU of a university-affiliated hospital, who were discharged or died between November 1, 2006 and June 30, 2012. During the study period, 10,642 patients were admitted at least once to the ICU. Of these patients, 4079 (38.3%) received red blood cells (RBCs), plasma or platelets in the ICU. The ICU mortality rate was 28.1% and in-hospital mortality rate was 32.3%. Among 39,591 blood product units transfused over the course of the study in the ICU (18,144 RBC units, 16,920 plasma units and 4527 platelet units), 46.2% were administered to patients who later died within the same hospitalization (41.2% of RBCs, 50.4% of plasma and 50.8% of platelets). Of all blood product units (RBCs, plasma and platelets) administered in the ICU over the study period, 11% were given within the last 24 hours before death. A large proportion of blood products used in the ICU are administered to patients who ultimately succumb to their illness in hospital, and many of these blood units are given in close proximity to death.
url http://europepmc.org/articles/PMC4575028?pdf=render
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