Small RNA Expression Profiling by High-Throughput Sequencing: Implications of Enzymatic Manipulation

Eukaryotic regulatory small RNAs (sRNAs) play significant roles in many fundamental cellular processes. As such, they have emerged as useful biomarkers for diseases and cell differentiation states. sRNA-based biomarkers outperform traditional messenger RNA-based biomarkers by testing fewer targets...

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Bibliographic Details
Main Authors: Fanglei Zhuang, Ryan T. Fuchs, G. Brett Robb
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Nucleic Acids
Online Access:http://dx.doi.org/10.1155/2012/360358