Genetically Predicted C-Reactive Protein Associated With Postmenopausal Breast Cancer Risk: Interrelation With Estrogen and Cancer Molecular Subtypes Using Mendelian Randomization

Genetically Predicted C-Reactive Protein Associated With Postmenopausal Breast Cancer Risk: Interrelation With Estrogen and Cancer Molecular Subtypes Using Mendelian Randomization

BackgroundImmune-related etiologic pathways that influence breast cancer risk are incompletely understood and may be confounded by lifestyles or reverse causality. Using a Mendelian randomization (MR) approach, we investigated the potential causal relationship between genetically elevated C-reactive...

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Bibliographic Details
Main Authors: Su Yon Jung, Jeanette C. Papp, Eric M. Sobel, Matteo Pellegrini, Herbert Yu, Zuo-Feng Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Oncology
Subjects:
genetically driven C-reactive protein
Mendelian randomization
obesity
exogenous estrogen
breast cancer subtypes by hormone receptor and HER2/neu
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.630994/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.630994/full

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